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Oscar De La Hoya out of retirement, announces on Lopez (Video)

Nov 19, 2009, 3:08 GMT

The Golden Boy and American boxing great, Oscar De La Hoya, makes the biggest announcement of his career live on 'Lopez Tonight.' ... more

Lopez reveals Larry David not as Jewish as we thought

Nov 13, 2009, 17:31 GMT

George Lopez is diving into the Human Genome work that National Geographic made popular in their documentaries this past year. ... more

Lopez Tonight opens with Carlos Santana

Nov 9, 2009, 16:13 GMT

Carlos Santana will be George's guest on TBS’s New Late-Night Series 'Lopez Tonight' premiering Monday, Nov. 9. ... more

Owen Wilson loves his 'Marmaduke'

Nov 3, 2009, 19:01 GMT

Owen Wilson has signed on to voice the famous Great Dane 'Marmaduke,' Fox's live-action/CG adaptation of the popular comic strip. ... more

Eva Longoria Parker and George Lopez host Almas

Jul 28, 2009, 4:39 GMT

While you were doing Sudoku, George Lopez has been taking over. ... more